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Leo Grady, PHD: Founder and CEO of Jona

Updated: Sep 15

Episode 74: Decode Your Gut with AI: Inside Jona Health’s Deep Shotgun Microbiome Test with the Founder Leo Grady


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🎙️ Episode Summary


Your gut health impacts everything—from digestion and immunity to brain clarity, energy levels, and even longevity. But here’s the problem: most stool tests on the market don’t give you the full picture.


In this episode of the BiohackerBlondie Podcast, Jenny sits down with Leo, co-founder of Jona, to uncover how the most advanced stool testing technology available is changing the game for gut health diagnostics.


Jona is on a mission to make microbiome analysis radically more accurate and actionable. Using cutting-edge metagenomic sequencing, their tests go beyond the limited scope of traditional 16S rRNA tests—identifying bacteria, fungi, viruses, and even keystone species with an unprecedented level of detail. That data is then paired with AI-driven analysis to generate a personalized roadmap to better health, from food recommendations to targeted supplementation strategies.


If you’ve been dealing with symptoms like bloating, fatigue, brain fog, skin issues, or stubborn health plateaus—or if you simply want to optimize your longevity, immunity, and resilience—this episode gives you the tools and knowledge to finally get answers that make a difference.


🔬 What You’ll Learn


🧬 Why Jona is Different


  • Beyond standard testing: How metagenomic sequencing delivers a far more complete view of your microbiome than traditional stool tests.

  • Keystone species: What they are, why they’re critical for gut health, and what happens when they go missing.

  • The role of AI-powered analysis in translating raw microbiome data into clear, actionable protocols.


🌱 Gut Health and Whole-Body Wellness


  • How microbiome diversity influences immune strength, inflammation, and disease prevention.

  • The gut-brain connection: how microbiome imbalances can trigger anxiety, depression, or brain fog.

  • The surprising ways gut health impacts hormonal balance, metabolism, and skin health.


📊 From Data to Results

  • How Jona Health’s reports make it easy to take action—with tailored diet, lifestyle, and supplement recommendations.

  • Real-world case studies of clients who’ve seen dramatic improvements using Jona’s approach.

  • How to track your progress over time and continually refine your gut health strategy.


💡 Practical Tips You Can Start Now


  • The best foods for feeding a healthy, diverse microbiome.

  • Daily habits that harm your gut (and what to do instead).

  • How stress management and sleep play an essential role in microbiome balance.


🧬 Key Takeaways


  • Advanced testing leads to better health decisions. By mapping your microbiome in detail, you can pinpoint the root causes of symptoms instead of guessing.

  • Gut health is foundational to longevity. Optimizing your microbiome supports immunity, cognition, energy, and overall vitality.

  • You can’t fix what you don’t measure. Accurate, in-depth testing is the missing link in most people’s health journeys.


Products & Tools Mentioned


  • Jona Health Advanced Stool Test – Full-spectrum microbiome analysis using metagenomic sequencing.

  • Personalized Gut Health Protocol – AI-generated recommendations for diet, lifestyle, and supplementation.

  • Prebiotic- and probiotic-rich foods for microbiome diversity.

  • Functional health strategies for restoring gut balance.


Special Offer for Listeners


Visit jona.health to learn more about their advanced microbiome testing and how it can transform your gut health.



Available on Spotify, Apple Podcasts, Amazon Music, and all major platforms.


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