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Dr. Sheldon Jordan, Artist, Innovator, Neurological Expert

Updated: Sep 23

Episode 37: Unlocking Brain Health: Advanced Imaging, Aging, Alzheimer's, Pain Management, and Cutting-Edge Therapies with Dr. Sheldon Jordan




The Brain’s Blueprint: Advanced Imaging, Exosome Therapy, and Alzheimer’s Breakthroughs with Dr. Sheldon Jordan


Episode Overview:


In this follow-up episode, Jenny Jones sits down with Dr. Sheldon Jordan to dive even deeper into the complexities of brain health. Dr. Jordan, a world-renowned neurologist, discusses the latest innovations in advanced brain imaging, techniques to reverse brain aging, and potential solutions for conditions like Alzheimer's and Parkinson’s. This episode covers everything from how inflammation impacts the brain to the potential of exosomes and ultrasound to heal concussions and enhance brain function. Dr. Jordan also shares his insights into optimizing brain health through supplements, lifestyle changes, and groundbreaking therapies.


Topics Covered:


Advanced Brain Imaging:


  • Routine MRI Scans vs. Advanced Imaging: Dr. Jordan explains how newer, advanced MRI imaging techniques can now detect brain function, connectivity, and chemistry, not just size and shape. This breakthrough allows for better-targeted treatments based on vascular, mitochondrial, or inflammatory brain issues.


  • Brain Drainage Systems: Discover how imaging can reveal clogging in brain drainage systems and toxic build-ups, potentially identifying the root cause of cognitive issues.


  • Individualized Treatment Plans: By using advanced scans, clinicians can tailor treatments to an individual's brain needs, reducing guesswork in choosing therapies and supplements.


Exosome Therapy:


  • Acute Brain Injuries: Dr. Jordan discusses the promising role of exosome therapy for treating concussions and head trauma. He shares ongoing research that shows how administering exosomes early can drastically improve recovery from post-concussion symptoms like memory loss, headaches, and sleep disturbances.


  • Alzheimer’s and Parkinson’s Disease: While exosomes for chronic conditions like Alzheimer's and Parkinson's are still in the clinical trial phase, Dr. Jordan shares optimism that this technology could soon reset brain aging and combat neurodegenerative diseases.


Focused Ultrasound and Transcranial Magnetic Stimulation (TMS):


  • Non-invasive Treatments: These therapies aim at brain areas responsible for memory, mood, and cognition, showing promise in reducing anxiety, depression, and neurological inflammation.


Supplements and Nutritional Recommendations for Brain Health:


  • NAD, NAC, and CoQ10: These supplements support mitochondrial function, helping cells produce more energy and potentially rejuvenating brain health.


  • Butyrate: As a key supplement to seal the gut lining, butyrate prevents gut toxins from entering the brain and causing inflammation.


  • Omega-3 Fatty Acids vs. Plasmalogens: Dr. Jordan emphasizes the importance of plasmalogens, a fatty compound critical for brain cell function, in comparison to typical omega-3 supplements.


Notable Guests and Research References:


  • Dr. Dongsheng Cai’s Mouse Experiment: Research at Albert Einstein College of Medicine showing how hypothalamic cells control aging.


  • Dr. Sabine Hazan: Leading gastroenterologist mentioned for her work on the gut biome and its impact on brain health.


  • Prodrom Sciences: A leading provider of plasmalogen supplements that Dr. Jordan recommends to support brain health and combat neurodegeneration.


Medical Concepts Discussed:


  • Amyloid Plaques in Alzheimer’s Disease: Dr. Jordan explains how amyloid acts as a “flytrap” in the brain, catching harmful microbes but leading to inflammation.


  • Tau Tangles: Learn how these protein tangles form inside cells during Alzheimer's and how they propagate damage across the brain.


  • Leaky Gut and Brain Inflammation: Dr. Jordan emphasizes the connection between gut health and brain function, advising the use of probiotics and butyrate to prevent brain inflammation.


  • Zombie Cells: Older cells that fail to die and contribute to chronic inflammation in the brain, accelerating the aging process.


Future of Brain Health:


  • Plasmalogen and Omega-3 Supplements: Dr. Jordan shares promising findings about plasmalogens and their role in preventing cognitive decline, especially in individuals with genetic risk factors for Alzheimer's (like ApoE4).


  • COVID-19 and Brain Health: Long-term effects of COVID-19 and its vaccines on brain inflammation, cognitive decline, and fatigue are discussed, with therapies like immunoglobulins and plasmapheresis showing promise.


Recommended Supplements:


  • Plasmalogen Precursor: For supporting brain membranes and reducing risk of Alzheimer’s.

  • NAD and CoQ10: For mitochondrial function and energy production

  • Curcumin Extracts: Anti-inflammatory agent for brain health, especially Theracurmin HP and Prodrome BDMC.

  • Butyrate: To seal leaky gut and prevent inflammation.

  • Melatonin: Critical for maintaining the biological clock in the hypothalamus.


Conditions Discussed:


  • Alzheimer’s Disease: Insights into amyloid plaques, tau tangles, and groundbreaking therapies to combat this degenerative disease.

  • Parkinson’s Disease: Links between brain function, gut health, and potential treatments like mucuna pruriens and exosome therapy.

  • Concussions: How early intervention with exosomes could significantly improve recovery outcomes.


Where to Find Dr. Jordan:



For supplements, simply follow the Fullscript link provided.


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