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Dr. Jonathann Kuo: Founder of Extension Health

Updated: 4 days ago

Episode 71: How the Top 1% Are Reversing Aging, Tracking Biomarkers & Optimizing Their Health — Inside Extension Health with Dr. Jonathann Kuo (What You Should Be Doing Now to Live Longer, Feel Better, and Prevent Disease)


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Episode Summary:

In this episode of the BiohackerBlondie Podcast, host Jenny Jones sits down with Dr. Jonathann Kuo, a board-certified pain management and regenerative medicine expert and founder of Extension Health, a concierge longevity optimization platform built for high performers.


From billionaires and CEOs to athletes and tech founders, Dr. Kuo reveals what the top 1% are doing to not only live longer—but feel sharper, stronger, and more energized as they age. This isn’t about waiting for disease to happen—it’s about testing, tracking, and turning back the biological clock with precision tools used at the cutting edge of regenerative medicine.


Whether you’re a peak performer or just someone looking to live better for longer, this episode uncovers tools, labs, peptides, and protocols you can use right now to extend your healthspan.


🔬 What You’ll Learn:


Why Extension Health Exists:


  • Dr. Kuo founded Extension Health to offer elite-level health optimization services, driven by data—not guesswork.

  • The platform blends concierge medicine with cutting-edge technology to provide preventative longevity care that’s customized.


What the Top 1% Are Doing:


  • The 1% don’t wait until something breaks—they continuously test and intervene early to stay mentally and physically sharp.

  • Dr. Kuo treats executives, founders, doctors, and professional athletes who want to optimize for brain performance, energy, recovery, and long-term vitality.


📈 Advanced Testing & Protocols Used at Extension Health:


  • Biological Age Testing – via DNA methylation and aging clocks

  • DEXA Scans – for body composition and visceral fat

  • VO₂ Max Testing – a key predictor of longevity

  • Micronutrient Panels – to identify deficiencies

  • Hormone Panels – testosterone, thyroid, DHEA

  • Inflammatory Markers – hs-CRP, homocysteine

  • Continuous Glucose Monitoring (CGM) – real-time metabolic data


💉 Longevity Tools, Therapies, and Interventions:


  • NAD+ IVs – to restore mitochondrial function and slow cellular aging

  • Exosome Therapy – signaling particles to regenerate tissue

  • Stem Cells (offshore) – for orthopedic and systemic rejuvenation

  • Peptides – including BPC-157, TB-500, and MOTS-c

  • Red Light Therapy & Photobiomodulation

  • Ozone Therapy

  • Hyperbaric Oxygen Therapy (HBOT)


💊 Top Supplements Mentioned:


  • Omega-3s – for cardiovascular and brain health

  • CoQ10 (Ubiquinol) – mitochondrial support

  • Vitamin D – foundational for immunity and inflammation

  • Creatine – for muscle mass and brain energy

  • Magnesium – for hundreds of cellular functions

  • Berberine – for glucose control

  • Urolithin A – supports mitochondrial mitophagy

  • NMN & NR – NAD+ precursors for energy and DNA repair


🧬 Key Lifestyle Habits of the Longevity-Focused:


  • Consistent resistance training

  • Prioritizing deep sleep and circadian rhythm

  • Breathwork and cold exposure to build resilience

  • Functional nutrition and protein optimization

  • Regular lab testing every 6 months

  • Use of wearables like CGMs and VO₂ monitors for real-time tracking


👥 Mentions & Resources:


  • Dr. Khan – for IV optimization

  • “Golden Bag” IV – a custom NAD+ IV blend with CoQ10, trace minerals, and glutathione

  • Extension Health – extension.health

  • Hyperbaric Centers – nationwide access

  • DEXA & VO₂ Labs – used to track body and aerobic metrics

  • Dr. Jonathann Kuo’s Clinic – personalized optimization care for high performers



Available on Spotify, Apple Podcasts, and all major platforms.


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