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Sep 273 min read

Dr. Chris Rhodes Founder of Mimio

Updated: 4 days ago

Episode 39: Backed by Clinical Research: Dr. Chris Rhodes, PhD, on the Supplement That Mimics a 36-Hour Fast While Still Eating




Episode Overview:


In this episode of the Biohacker Blondie podcast, Jenny Jones interviews Dr. Chris Rhodes, PhD in Nutritional Biochemistry and the founder of Mimio Health. Dr. Rhodes shares his journey from Stanford and UC Davis to founding Mimio, a clinically-backed supplement designed to mimic the benefits of a 36-hour fast without actually fasting. He delves into the science of fasting, longevity, and how specific molecules produced during fasting can now be supplemented to activate pro-longevity bio-pathways.


Topics Covered:


The Science of Fasting and Longevity:


  • Fasting and Lifespan Extension: How fasting not only extends lifespan in animal models but also improves healthspan by reducing inflammation, improving metabolic health, and preventing age-related diseases.

  • Metabolic Switch and Autophagy: The body’s metabolic shift after 24 hours of fasting, moving from glycogen to fat-burning mode, which triggers autophagy and cellular regeneration.

  • Anti-inflammatory and Antioxidant Effects: Dr. Rhodes explains how fasting can reduce inflammation, improve antioxidant capacity, and protect against metabolic damage.


Mimio Supplement and Clinical Research:


  • Fast-Mimicking Supplement: Mimio mimics a 36-hour fast using four key fasting metabolites: OEA, niacinamide (B3), and two other molecules upregulated during fasting, as discovered in clinical trials.

  • Clinical Study Results: Dr. Rhodes describes how Mimio replicates fasting benefits, such as reducing biological age, improving cholesterol, testosterone, and other key biomarkers in just 8 weeks.

  • Pilot Study: Mimio was shown to prevent the typical post-meal pro-inflammatory response, maintaining health benefits while eating.


Appetite Control and Fasting Support:


  • Hunger Suppression: One of the molecules in Mimio, OEA (oleoylethanolamide), helps reduce hunger and promote fat breakdown, making it easier to fast or reduce calorie intake.

  • Fasting Hacks for Beginners: Dr. Rhodes shares how to ease into fasting by skipping meals and gradually extending fasting windows, with the help of Mimio to curb hunger and maintain energy.


Biohacks for Health and Longevity:


  • Cold Exposure: Dr. Rhodes emphasizes the benefits of cold plunges or cold showers for boosting metabolic flexibility and stress resilience.

  • Dopamine Fasting and Tech Detox: Unplugging from screens to enhance mental clarity and lower stress, another biohack that Dr. Rhodes practices regularly.


Supplements and Nutrition for Fasting:


  • Niacinamide (B3) vs. NR/NMN: Dr. Rhodes explains why he chose niacinamide over NR or NMN for Mimio, based on its specific role in fasting and longevity pathways.

  • Other Fasting Hacks: Apple cider vinegar and konjac (shirataki) noodles are among Dr. Rhodes' favorite ways to manage hunger and improve metabolic health during fasting.


Where to Find Dr. Chris Rhodes and Mimio Health:


  • Mimio Health: Available at MimioHealth.com, Mimio offers the benefits of fasting in a convenient supplement form. The company is also expanding to Amazon and select longevity clinics in the near future.

  • TikTok: Follow Dr. Chris Rhodes on TikTok at @ThatNutritionDr for fasting tips, nutrition hacks, and more.


Closing Thoughts: Dr. Chris Rhodes emphasizes the importance of both scientific research and personal experience in the development of Mimio. His work highlights how fasting and the right supplementation can lead to significant improvements in longevity and health. Whether you're a seasoned biohacker or new to fasting, this episode offers valuable insights into how you can optimize your health.


Recommendations:


  • Mimio Health – Fasting mimetic supplement designed to activate longevity pathways.

  • Apple cider vinegar – Helps manage blood sugar and reduce hunger.

  • Konjac (shirataki) noodles – A low-calorie, high-fiber option for improving satiety during fasting. Miracle Noodles


Extra Links



Disclaimer: This program has not been evaluated or approved by the FDA. The comments within this presentation are not be taken as advice or treatment for any condition or disease, and are being presented for the purposes of discussion and education only. The information provided in this podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare professional before making any health decisions or starting any new treatments.



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